Rueckert-Hartman College for Health Professions
Doctor of Nursing Practice
Thesis - Open Access
Number of Pages
Genital Ureaplasma is a worldwide issue in obstetrics and gynecology. Morbidities can include pelvic inflammatory disease, infertility, miscarriage, preterm delivery, and chorioamnionitis, if left untreated. The quality improvement (QI) initiative used a retrospective chart review of 128 subjects, collecting data of antibiotic treatment differences and recurrence of genital Ureaplasma at a corporate owned obstetrical and gynecologic outpatient clinic in the metro-Denver area. The investigator used the percentage change mathematical formula to determine the percentage difference between patient antibiotic treatment only with symptomatic genital Ureasplasma versus antibiotic treatment of the patient and the partner. Overall, the project did not show statistical difference between the two variables (percentage change of 14.47%). However, unintentional findings were reported on the recurrence difference between patient and patient and partner treatment between the antibiotics doxycycline (20.7% and 16.57%), azithromycin (50.07% and 50.7%), and clindamycin (100% recurrence rate with and without partner treatment). The major limitation of this project was the small sample size. The most significant implication of this project was that the antibiotic findings were consistent with CDC and UpToDate guidelines. It appeared that doxycycline has a higher success rate for treatment of genital Ureaplasma. Further investigation is recommended.
Date of Award
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Paul, Shelbie, "Considerations of Antibiotic Treatment for Genital Ureaplasma" (2020). Student Publications. 980.