First Advisor

Kathleen Whalen


Rueckert-Hartman College for Health Professions

Degree Name

Doctor of Nursing Practice


Loretto Heights

Document Type

Thesis - Open Access

Number of Pages

67 pages


Genital Ureaplasma is a worldwide issue in obstetrics and gynecology. Morbidities can include pelvic inflammatory disease, infertility, miscarriage, preterm delivery, and chorioamnionitis, if left untreated. The quality improvement (QI) initiative used a retrospective chart review of 128 subjects, collecting data of antibiotic treatment differences and recurrence of genital Ureaplasma at a corporate owned obstetrical and gynecologic outpatient clinic in the metro-Denver area. The investigator used the percentage change mathematical formula to determine the percentage difference between patient antibiotic treatment only with symptomatic genital Ureasplasma versus antibiotic treatment of the patient and the partner. Overall, the project did not show statistical difference between the two variables (percentage change of 14.47%). However, unintentional findings were reported on the recurrence difference between patient and patient and partner treatment between the antibiotics doxycycline (20.7% and 16.57%), azithromycin (50.07% and 50.7%), and clindamycin (100% recurrence rate with and without partner treatment). The major limitation of this project was the small sample size. The most significant implication of this project was that the antibiotic findings were consistent with CDC and UpToDate guidelines. It appeared that doxycycline has a higher success rate for treatment of genital Ureaplasma. Further investigation is recommended.

Date of Award

Fall 2020

Location (Creation)

Colorado (state); Denver (county); Denver (inhabited place)

Rights Statement

All content in this Collection is owned by and subject to the exclusive control of Regis University and the authors of the materials. It is available only for research purposes and may not be used in violation of copyright laws or for unlawful purposes. The materials may not be downloaded in whole or in part without permission of the copyright holder or as otherwise authorized in the “fair use” standards of the U.S. copyright laws and regulations.